Aprepitant Impurity 32 CAS 225920-05-8
| CAS No. | 225920-05-8 |
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Aprepitant Impurity 32 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Aprepitant Impurity 32 (CAS 225920-05-8), a pharmacopoeial impurity reference standard (molecular formula C10H8F6O, MW 258.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Aprepitant Impurity 32 (C10H8F6O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Halogen Content | F-containing |
Related Aprepitant Standards
- Aprepitant Impurity 33 (CAS 1265177-56-7)
- Aprepitant Impurity 38 (CAS 127852-28-2)
- Aprepitant Impurity 45 (CAS 364-47-6)
- Aprepitant Impurity 76 (CAS CATO-C4X-114176)
- Aprepitant impurity 28 (CAS 479679-98-6)
- Aprepitant Impurity 34 (CAS 30071-93-3)
- Aprepitant Impurity 75 (CAS 240489-98-9)
- Aprepitant impurity 50 (CAS 349-59-7)
Recommended Standards
- N1-(5-bromopyridin-2-yl)pentane-1,5-diamine (CAS 199522-81-1)
- Hexafluoro-2-(4-methylphenyl)propan-2-ol (CAS 2010-61-9)
- 5,6,7,8-Tetrahydronaphthalene-2-boronic Acid Pinacol Ester (CAS 627526-54-9)
- 4,4,5,5-Tetramethyl-2-(5,6,7,8-tetrahydronaphthalen-1-yl)-1,3,2-dioxaborolane (CAS 929031-44-7)
- Tryptophan impurity 41 (CAS CATO-C4X-137341)
- Vazegepant Impurity 19 (CAS 2923756-41-4)
- Dexpanthenol Impurity 29 (CAS 1112-33-0(Free acid)
- Ethyl 3-(4-hydroxy-3,5-diiodophenyl)propanoate (CAS 189447-39-0)
- H-Met-Met-Met-OH (CAS 14486-15-8)
- 3-(2-Carboxyethyl)-4-chloro-1H-indole-2-carboxylic acid (CAS 130798-49-1)
- 1-(Butan-2-yl)-1h-pyrazole-5-sulfonyl chloride (CAS 1245808-44-9)
- 5,5-Dimethyl-2,4,5,6-tetrahydrocyclopenta[c]pyrrole-1-carboxylic acid (CAS 535170-14-0)
- 2,4-Dichloro-6-methylcinnamic acid (CAS 1807415-79-7)
- Liraglutide Impurity 6 TFA Salt (CAS CATO-C4X-19926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com