2-((2-Chloropyrimidin-4-yl)amino)-2-phenylethan-1-ol CAS 1482228-67-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1482228-67-0
Molecular FormulaC12H12ClN3O
Molecular Weight249.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((2-Chloropyrimidin-4-yl)amino)-2-phenylethan-1-ol CAS 1482228-67-0 chemical structure

Description

The occurrence of 2-((2-Chloropyrimidin-4-yl)amino)-2-phenylethan-1-ol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-((2-Chloropyrimidin-4-yl)amino)-2-phenylethan-1-ol (CAS 1482228-67-0), a certified reference material (molecular formula C12H12ClN3O, MW 249.70 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-((2-Chloropyrimidin-4-yl)amino)-2-phenylethan-1-ol is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 249.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H12ClN3O
Molecular Weight249.70 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl-containing
Nitrogen Atoms3

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