Pitavastatin Impurity 18 CAS 148516-11-4
| CAS No. | 148516-11-4 |
| Molecular Formula | C21H18FNO2 |
| Molecular Weight | 335.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pitavastatin Impurity 18 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Pitavastatin Impurity 18 (CAS 148516-11-4), molecular formula C21H18FNO2 and molecular weight 335.37 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Pitavastatin Impurity 18 (C21H18FNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 335.37 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Pitavastatin Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18FNO2 |
| Molecular Weight | 335.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Pitavastatin Standards
- Pitavastatin Impurity 41 (CAS CATO-C4X-103741)
- Pitavastatin Impurity 78 (CAS CATO-C4X-103778)
- Pitavastatin Impurity 40 (CAS 121659-86-7)
- Pitavastatin Impurity 21 (CAS 154057-56-4)
- Pitavastatin Impurity 42 (CAS CATO-C4X-103742)
- Pitavastatin Impurity 43 (CAS CATO-C4X-103743)
- Pitavastatin Impurity 85 (CAS CATO-C4X-103785)
- Pitavastatin Hydroxymethyl Impurity (CAS 24922-02-9)
Recommended Standards
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