(2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 1486470-94-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1486470-94-3
Molecular FormulaC6H8F3NO2
Molecular Weight183.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 1486470-94-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 183.13 g/mol gives (2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1486470-94-3) is a high-purity analytical reference standard with the molecular formula C6H8F3NO2 and a molecular weight of 183.13 g/mol.

The molecular framework of (2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (C6H8F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H8F3NO2
Molecular Weight183.13 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms1

Recommended Standards

Why CATO?