Methyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)thiophene-2-carboxylate CAS 338756-06-2
| CAS No. | 338756-06-2 |
| Molecular Formula | C12H7ClF3NO3S |
| Molecular Weight | 337.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)thiophene-2-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)thiophene-2-carboxylate (CAS 338756-06-2) is a high-purity analytical reference standard with the molecular formula C12H7ClF3NO3S and a molecular weight of 337.70 g/mol.
Methyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)thiophene-2-carboxylate (C12H7ClF3NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF3NO3S |
| Molecular Weight | 337.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Methyl 4-amino-3-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)isothiazole-5-carboxylate (CAS 1823182-74-6)
- 2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-ethoxyacetamide (CAS 1181533-47-0)
- Methyl 3-bromo-1H-pyrrolo[2,3-c]pyridine-7-carboxylate (CAS 1403821-67-9)
- 2-Amino-4H-pyrido[1,2-a][1,3,5]triazin-4-one (CAS 502165-01-7)
- (+)-Nortrachelogenin (CAS 61521-74-2)
- 5-Amino-6-nitroso-7H-thiazolo[3,2-a]pyrimidin-7-one (CAS 174279-85-7)
- 4-Bromo-5-chloro-2-fluorophenol (CAS 1805518-69-7)
- 2-(Cyclopropylsulfonyl)-1H-indole (CAS 1505521-44-7)
- N-(5-((4-Nitrobenzyl)thio)-1,3,4-thiadiazol-2-yl)-3-phenylpropanamide (CAS 476464-69-4)
- 2-Bromo-4-methyl-1-[(2-methylprop-2-en-1-yl)oxy]benzene (CAS 110124-11-3)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
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