(E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine CAS 478078-92-1
| CAS No. | 478078-92-1 |
| Molecular Formula | C15H11BrFNO3 |
| Molecular Weight | 352.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 352.16 g/mol gives (E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine (CAS 478078-92-1), molecular formula C15H11BrFNO3 and molecular weight 352.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine (C15H11BrFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11BrFNO3 |
| Molecular Weight | 352.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- Methyl 2-(2-(3-bromo-4-fluorophenyl)acetyl)nicotinate (CAS 1036402-42-2)
- Methyl 4-((5-bromo-2-hydroxybenzylidene)amino)-3-fluorobenzoate (CAS 1296225-21-2)
- 2-(4-Bromo-2-formylphenoxy)-N-(4-fluorophenyl)acetamide (CAS 553673-99-7)
- 7-Bromo-2-(3-fluoro-4-methoxyphenyl)-5-methoxy-1,3-benzoxazole (CAS 544704-75-8)
- 4-Bromo-2-phenyl-8-(trifluoromethyl)quinoline (CAS 1189105-98-3)
- Methyl 6-bromo-3-((4-methoxybenzyl)oxy)picolinate (CAS 1235142-74-1)
- 5-Bromo-2-(naphthalen-2-yl)isoindoline-1,3-dione (CAS 82104-05-0)
- 2-Bromo-4-methoxy-3-(4-nitrophenoxy)benzaldehyde (CAS 685873-72-7)
Recommended Standards
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(4-(trifluoromethyl)benzyl)-1H-pyrazole (CAS 1853185-17-7)
- 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole (CAS 1604036-75-0)
- 3-(trifluoromethyl)phenyl 2,5-dichloropyridine-3-carbothioate (CAS 266692-08-4)
- 1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole (CAS 1486485-54-4)
- 1-(4-Bromo-2-fluorophenyl)cyclobutanecarbonitrile (CAS 749929-04-2)
- 2-(2-Chloropyridin-3-yl)-1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazole (CAS 338411-21-5)
- 2-Bromo-4-(tert-butyl)phenyl 3-pyrrolidinylmethyl-ether hydrochloride (CAS 1219948-97-6)
- Daprodustat Impurity 22 (CAS CATO-C4X-240722)
- 2,4-Diamino-6-ethylpyrimidin-5-ol (CAS 83403-29-6)
- Dmst (CAS 66840-71-9)
- 3-amino-4-chloro-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1006451-86-0)
- 9-chloro-7,10-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),2(6),8,10-tetraene (CAS 1279717-10-0)
- (1-(3-Methoxybenzyl)-1h-imidazol-4-yl)methanamine hydrochloride (CAS 1439902-60-9)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com