4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole CAS 1604036-75-0
| CAS No. | 1604036-75-0 |
| Molecular Formula | C17H20BF3N2O2 |
| Molecular Weight | 352.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole.
4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole (CAS 1604036-75-0), molecular formula C17H20BF3N2O2 and molecular weight 352.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole (C17H20BF3N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H20BF3N2O2 |
| Molecular Weight | 352.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Tetramethyl Standards
- 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(3-trifluoromethyl-benzyl)-1H-pyrazole (CAS 1415825-08-9)
- 1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole (CAS 1486485-54-4)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(4-(trifluoromethyl)benzyl)-1H-pyrazole (CAS 1853185-17-7)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl trifluoromethanesulfonate (CAS 1027059-48-8)
- 3'-Methyl-4'-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-carboxylic acid methyl ester (CAS 1411993-04-8)
- N-(4-((3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)phenyl)acetamide (CAS 1201644-31-6)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(m-tolyl)urea (CAS 765949-02-8)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(o-tolyl)urea (CAS 935660-79-0)
Recommended Standards
- (E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine (CAS 478078-92-1)
- Methyl 4-((5-bromo-2-hydroxybenzylidene)amino)-3-fluorobenzoate (CAS 1296225-21-2)
- 2-(4-Bromo-2-formylphenoxy)-N-(4-fluorophenyl)acetamide (CAS 553673-99-7)
- Methyl 2-(2-(3-bromo-4-fluorophenyl)acetyl)nicotinate (CAS 1036402-42-2)
- Tert-butyl 4-(1-(ethoxycarbonyl)cyclopropyl)piperidine-1-carboxylate (CAS 1363382-33-5)
- Ethyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate (CAS 19397-74-1)
- tert-Butyl 2-(6-methoxy-2-methylpyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352483-50-1)
- (2E)-3-(Pyrrolidin-1-yl)-N-[4-(trifluoromethyl)phenyl]but-2-enamide (CAS 134888-97-4)
- 2-(2-Methoxy-5-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)acetic acid (CAS 294860-96-1)
- (4-(Difluoromethyl)-1-methyl-1H-pyrazol-3-yl)methanamine (CAS 1801270-15-4)
- 4-(3-Chlorophenyl)-3-methyl-1h-pyrazol-5-amine (CAS 62538-18-5)
- 7-Methoxy-5-methyl-1H-indazole (CAS 1360886-36-7)
- 3-(3-ethyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol hydrochloride (CAS 1803606-50-9)
- Semaglutide impurity 76 (CAS CATO-C4X-222676)
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