Tamsulosin Impurity 28 CAS 1495375-67-1
| CAS No. | 1495375-67-1 |
| Molecular Formula | C8H12N2O3S |
| Molecular Weight | 216.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tamsulosin Impurity 28 (CAS 1495375-67-1) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N2O3S and a molecular weight of 216.26 g/mol.
The molecular framework of Tamsulosin Impurity 28 (C8H12N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tamsulosin Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O3S |
| Molecular Weight | 216.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Tamsulosin Standards
- Tamsulosin EP Impurity E (CAS 105764-07-6)
- Tamsulosin Impurity 15 (CAS 92119-04-5)
- Tamsulosin Impurity 16 (CAS 21003-56-5)
- Tamsulosin Impurity 17 (CAS 21003-57-6)
- Tamsulosin Impurity 18 (CAS CATO-C4X-118718)
- Tamsulosin Impurity 31 (CAS 4463-59-6)
- Tamsulosin Impurity 30 (CAS 589-10-6)
- Tamsulosin Impurity 77 (CAS 1510621-28-9)
Recommended Standards
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- (2E)-1-[4-(2-Fluorophenyl)piperazin-1-yl]-3-phenylprop-2-en-1-one (CAS 546107-80-6)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
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