Amoxicillin EP Impurity A(Sulbactam EP Impurity B) CAS 551-16-6
| CAS No. | 551-16-6 |
| Molecular Formula | C8H12N2O3S |
| Molecular Weight | 216.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Amoxicillin EP Impurity A(Sulbactam EP Impurity B) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Amoxicillin EP Impurity A(Sulbactam EP Impurity B) (CAS 551-16-6), a pharmacopoeial impurity reference standard (molecular formula C8H12N2O3S, MW 216.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Amoxicillin EP Impurity A(Sulbactam EP Impurity B) (C8H12N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 216.26 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O3S |
| Molecular Weight | 216.26 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amoxicillin Standards
- Amoxicillin Impurity 100 (CAS CATO-C4X-1148100)
- Amoxicillin Impurity 107 (CAS CATO-C4X-1148107)
- Amoxicillin Impurity 28 (CAS 37727-80-3)
- Amoxicillin Impurity 85(Mixture) (CAS CATO-C4X-114885)
- Amoxicillin Impurity 41 (CAS CATO-C4X-114841)
- Amoxicillin Impurity 93 (CAS CATO-C4X-114893)
- Amoxicillin EP Impurity F (CAS 126247-63-0)
- rac-Amoxicillin EP Impurity H (CAS 106644-43-3)
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Why CATO?
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