Indocyanine Green Impurity 14 CAS 1497-49-0
| CAS No. | 1497-49-0 |
| Molecular Formula | C17H16N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Indocyanine Green Impurity 14.
CATO supplies Indocyanine Green Impurity 14 (CAS 1497-49-0), a pharmacopoeial impurity reference standard (molecular formula C17H16N2HCl, MW 284.79 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Indocyanine Green Impurity 14 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16N2 HCl |
| Molecular Weight | 284.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Indocyanine Standards
- Indocyanine Green Impurity 10 (CAS 109-70-6)
- Indocyanine Green Impurity 42 (CAS 1182721-75-0)
- Indocyanine Green Impurity 4 (CAS 1201170-49-1)
- Indocyanine Green Impurity 64 (CAS 1351043-94-1)
- Indocyanine Green Impurity 24 (CAS 13959-24-5)
- Indocyanine Green Impurity 27 (CAS 1563-87-7)
- Indocyanine Green-Succinimidyl Ester (CAS 1622335-40-3)
- Indocyanine Green Carboxylic Acid (CAS 181934-09-8)
Recommended Standards
- Tegoprazan Impurity 28 (CAS CATO-C4X-229728)
- Fluralaner impurity 45 (CAS CATO-C4X-218045)
- Maytansinoid Impurity 14 (CAS CATO-C4X-22514)
- 2-(2-Chloroacetamido)-n-(1-phenylethyl)benzamide (CAS 568577-54-8)
- 4-Chloro-2-(piperazin-1-yl)pyrimidine Hydrochloride (CAS 634469-41-3)
- 2'-Cyano-2,4'-difluorobiphenyl-5-boronic acid pinacol esters, 97% (CAS 660425-28-5)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxycarbonyl)phenyl)propanoic acid (CAS 183070-47-5)
- 2-[(prop-2-yn-1-yl)amino]-2-(2,4,6-trimethylphenyl)acetic acid hydrochloride (CAS 1796894-91-1)
- 3-(2-Methylthiazol-4-yl)acrylaldehyde (CAS 226940-34-7)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com