Avibactam Impurity 25 CAS 1501980-29-5
| CAS No. | 1501980-29-5 |
| Molecular Formula | C13H18N2O3 |
| Molecular Weight | 250.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 250.29 g/mol gives Avibactam Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Avibactam Impurity 25 (CAS 1501980-29-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H18N2O3 and a molecular weight of 250.29 g/mol.
Avibactam Impurity 25 (C13H18N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18N2O3 |
| Molecular Weight | 250.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 2 |
Related Avibactam Standards
- Avibactam Impurity 11 (CAS CATO-C4X-134811)
- Avibactam Impurity 23 (CAS 1416134-49-0)
- Avibactam Impurity 26 (CAS CATO-C4X-134826)
- Avibactam Impurity 44 (CAS CATO-C4X-134844)
- Avibactam Impurity 6(2S,5S) (CAS CATO-C4X-13486)
- Avibactam Impurity 85 (CAS 2733516-71-5)
- Avibactam impurity 111 (CAS CATO-C4X-1348111)
- Avibactam impurity 113 (CAS 115134-37-7)
Recommended Standards
- 4-isopropoxy-N1,N1-dimethylisophthalamide (CAS CATO-C3D-263041)
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- Amiodarone Impurity 38 (CAS 138320-26-0)
- Albendazole EP Impurity H (CAS CATO-C4X-153538)
- Blonanserin Impurity 20 (CAS CATO-C4X-111020)
- Canagliflozin Impurity 34 (CAS 32384-65-9)
- tert-Butyl (2S)-2-[(4-methylphenyl)sulfonyloxymethyl]morpholine-4-carboxylate (CAS 148638-76-0)
- 5-fluoro-1-(propan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole (CAS 2364586-39-8)
- Latanoprost EP Impurity E (CAS 145773-22-4)
- N-(4-tert-Butylphenyl)-3-chloro-1-benzothiophene-2-carboxamide (CAS 1004642-98-1)
- 3-(4-Chlorophenyl)-1-cyclopropylpiperazine (CAS 1248908-14-6)
- 2-((4-Chlorophenyl)sulfonyl)-1H-indole (CAS 1505521-32-3)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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