1-(2,2-Difluoroethyl)piperidine-4-carboxylic acid CAS 937602-78-3
| CAS No. | 937602-78-3 |
| Molecular Formula | C8H13F2NO2 |
| Molecular Weight | 193.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2,2-Difluoroethyl)piperidine-4-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2,2-Difluoroethyl)piperidine-4-carboxylic acid (CAS 937602-78-3), molecular formula C8H13F2NO2 and molecular weight 193.19 g/mol, is a CATO reference standard with documented purity and traceability.
1-(2,2-Difluoroethyl)piperidine-4-carboxylic acid (C8H13F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(2,2-Difluoroethyl)piperidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H13F2NO2 |
| Molecular Weight | 193.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)piperidine-2-carboxylic acid (CAS 1218200-72-6)
- Methyl 2-[1-(2,2-difluoroethyl)azetidin-3-yl]acetate (CAS 1432678-05-1)
- 4-(2,2-Difluoroethyl)piperidine-4-carboxylic acid (CAS 1503725-95-8)
- 1-(2,2-Difluoroethyl)piperidine-3-carboxylic acid (CAS 937602-80-7)
- 4-(1,1-Difluoroethyl)thiazole-2-carboxylic acid (CAS 1780878-51-4)
- 3-(1,1-difluoroethyl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1024599-54-9)
- 1-(1,1-Difluoroethyl)naphthalene (CAS 1204295-97-5)
- 2-(1,1-Difluoroethyl)naphthalene (CAS 1204296-00-3)
Recommended Standards
- 2-(Methylthio)-5-(trifluoromethyl)pyridine (CAS 650592-47-5)
- (S)-Methyl 2-(5,5-difluoropiperidin-3-yl)acetate (CAS 2761951-83-9)
- 2-(Trifluoromethylthio)aniline (CAS 347-55-7)
- (R)-Methyl 2-(5,5-difluoropiperidin-3-yl)acetate (CAS 2761951-94-2)
- Methyl 4-hydroxyindole-2-carboxylate (CAS 27748-08-9)
- 2-Chloro-1-(4-propylphenyl)ethan-1-one (CAS 105443-49-0)
- 2-Propylhexanoic Acid Methyl Ester (CAS 5162-60-7)
- Tert-butyl 3-((methylsulfonyl)methyl)azetidine-1-carboxylate (CAS 1824281-15-3)
- Galantamine Hydrobromide Racemic (CAS 193146-85-9)
- 1-(2,2-diethoxyethoxy)-2-methoxybenzene (CAS 161364-38-1)
- 1,3,3-Trichloro-1,1-difluoropropane (CAS 460-63-9)
- Lidocaine Impurity 6 (CAS 64585-18-8)
- Methyl 2,3,5-trichloro-4-methylbenzoate (CAS 203573-15-3)
- Neuropeptide Y (2-36) (human, rat) trifluoroacetate salt (CAS 123139-39-9)
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