Naproxen Impurity 53 CAS 150493-03-1

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.150493-03-1
Molecular FormulaC9H17ClO2
Molecular Weight192.68 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Naproxen Impurity 53 CAS 150493-03-1 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies Naproxen Impurity 53 (CAS 150493-03-1), a pharmacopoeial impurity reference standard (molecular formula C9H17ClO2, MW 192.68 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C9H17ClO2, Naproxen Impurity 53 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 192.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC9H17ClO2
Molecular Weight192.68 g/mol
Purity≥95%
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1999
Halogen ContentCl-containing

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