Dabigatran Impurity 93 CAS 7452-59-7
| CAS No. | 7452-59-7 |
| Molecular Formula | C9H17ClO2 |
| Molecular Weight | 192.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.68 g/mol gives Dabigatran Impurity 93 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Dabigatran Impurity 93 (CAS 7452-59-7, C9H17ClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H17ClO2, Dabigatran Impurity 93 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 192.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dabigatran Impurity 93 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17ClO2 |
| Molecular Weight | 192.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Dabigatran Standards
- Dabigatran Impurity 75 (CAS 355809-32-4)
- Dabigatran Impurity 68 (CAS 103041-38-9)
- Dabigatran Etexilate Impurity 84 (CAS 175867-55-7)
- Dabigatran Impurity 69 (CAS 41263-74-5)
- Dabigatran Impurity 78 (CAS 1369943-91-8)
- Dabigatran Impurity 83 (CAS 218168-58-2)
- Dabigatran Impurity 96 (CAS 16156-50-6)
- Dabigatran Impurity 103 (CAS CATO-C4X-1089103)
Recommended Standards
- propan-2-yl 6-chlorohexanoate (CAS 71195-77-2)
- Naproxen Impurity 53 (CAS 150493-03-1)
- Heptan-2-yl 2-chloroacetate (CAS 383412-05-3)
- Brivaracetam Impurity 83 (CAS CATO-C4X-200783)
- Brivaracetam Impurity 114 (CAS CATO-C4X-2007114)
- Menaquinone impurity 02 (CAS 65941-19-7)
- Atorvastatin Calcium EP Impurity F (CAS 887196-24-9)
- 2-(Isopropyl((1-methylpyrrolidin-3-yl)methyl)amino)acetic acid (CAS 1353944-84-9)
- (1-Ethylcyclobutyl)methanol (CAS 255721-49-4)
- {[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzyl]-methyl-amino}-acetic acid ethyl ester (CAS 1311280-39-3)
- 4-Bromo-5-(2-methylpropoxy)benzene-1,2-diamine (CAS 1373232-96-2)
- 1-(4-Fluorophenyl)cyclobutanecarboxylic Acid (CAS 151157-46-9)
- 2-[methyl(pyrazin-2-yl)amino]acetic acid (CAS 953740-40-4)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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