Tiotropium EP Impurity G CAS 1508-46-9
| CAS No. | 1508-46-9 |
| Molecular Formula | C9H16NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tiotropium EP Impurity G (CAS 1508-46-9), a pharmacopoeial impurity reference standard (molecular formula C9H16NO2Br, MW 250.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H16NO2Br, Tiotropium EP Impurity G contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 250.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H16NO2 Br |
| Molecular Weight | 250.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Tiotropium Standards
- Tiotropium Impurity 26 (CAS 10299-90-8)
- Tiotropium Bromide Impurity 8 Potassium Salt (CAS 10304-09-3)
- Tiotropium Bromide EP Impurity H (Mixture of Enantiomers) (CAS 1044148-31-3)
- Tiotropium Bromide EP Impurity H-d3 Bromide (Mixture of Enantiomers) (CAS 1044148-31-3（unlabeled）)
- Tiotropium-d6 (CAS 1126775-44-7)
- Tiotropium-D3 Bromide (CAS 1127226-56-5)
- Tiotropium Bromide EP Impurity B (CAS 136310-64-0)
- Tiotropium EP Impurity D (CAS 136310-66-2)
Recommended Standards
- Faropenem Impurity 21 (CAS CATO-C4X-128921)
- Flucloxacillin impurity 6 (CAS CATO-C4X-16476)
- Cefepime Dihydrochloride Monohydrate EP Impurity E (CAS 103296-32-8)
- bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl methanesulfonate (CAS 137337-73-6)
- 1-(4-{[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}phenyl)-1H-1,3-benzodiazole (CAS 685106-77-8)
- Ethyl 2-[[(4-chlorophenyl)-cyano-methyl]amino]acetate (CAS 1018259-22-7)
- 2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine (CAS 878733-59-6)
- (2S)-2-[(Phenylcarbamoyl)amino]propanoic acid (CAS 93850-62-5)
- Canrenoic Acid (CAS 4138-96-9)
- Insulin aspart (CAS 116094-23-6)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com