Roxadustat Impurity N5 CAS 1509958-20-6
| CAS No. | 1509958-20-6 |
| Molecular Formula | C20H17NO6 |
| Molecular Weight | 367.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Roxadustat Impurity N5 (CAS 1509958-20-6), a pharmacopoeial impurity reference standard (molecular formula C20H17NO6, MW 367.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Roxadustat Impurity N5 (C20H17NO6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 367.35 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17NO6 |
| Molecular Weight | 367.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 1 |
Related Roxadustat Standards
- Roxadustat impurity 134 (CAS 2243807-81-8)
- Roxadustat Impurity 101 (CAS CATO-C4X-2213101)
- Roxadustat Impurity 126 (CAS CATO-C4X-2213126)
- Roxadustat Impurity 5 (CAS 1421312-36-8)
- Roxadustat Impurity 74 (CAS CATO-C4X-221374)
- Roxadustat Impurity 132 (CAS CATO-C4X-2213132)
- Roxadustat Impurity 154 (CAS CATO-C4X-2213154)
- Roxadustat Impurity 34 (CAS CATO-C4X-221334)
Recommended Standards
- (S)-2-(2-((4-Methyl-2-oxo-2h-chromen-7-yl)oxy)acetamido)-2-phenylacetic acid (CAS 1243062-50-1)
- Ethyl 1-(4-phenylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 159885-61-7)
- 5-(4-Methoxyphenyl)-4-[4-(trifluoromethoxy)-phenyl]-4H-1,2,4-triazole-3-thiol (CAS 1171522-84-1)
- Acenocoumarol Impurity 10 (CAS 17298-36-1)
- Norfloxacin Impurity C25 (CAS 74011-47-5)
- ZHC-116 Impurity 7 (CAS CATO-C4X-23887)
- Delamanid Impurity 6 (CAS 1318735-00-0)
- 4-Bromo-1-fluoro-2-(hexyloxy)benzene (CAS 1772047-98-9)
- 6-Methoxy-4-nitro-1H-indazole-3-carbaldehyde (CAS 1000341-26-3)
- 5-Ethynylisoquinoline-4-carbaldehyde (CAS 2920713-07-9)
- 6-(sec-Butoxy)-2-((2-methoxyphenyl)thio)pyrimidin-4(3H)-one (CAS 284681-74-9)
- 3-((2-Hydroxy-3-methoxybenzyl)amino)-1H-pyrazole-4-carbonitrile (CAS 1027754-56-8)
- 1,3-Dibromo-4-iodo-5-methyl-2-nitrobenzene (CAS 1160573-65-8)
- Bonemarrow-Derived Mesenchymal Stem Cells Affinity Peptide trifluoroacetate salt (CAS 683750-83-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com