Norfloxacin Impurity C25 CAS 74011-47-5
| CAS No. | 74011-47-5 |
| Molecular Formula | C18H22FN3O3 |
| Molecular Weight | 347.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Norfloxacin Impurity C25 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Norfloxacin Impurity C25 (CAS 74011-47-5) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22FN3O3 and a molecular weight of 347.38 g/mol.
Norfloxacin Impurity C25 (C18H22FN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Norfloxacin Impurity C25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H22FN3O3 |
| Molecular Weight | 347.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Norfloxacin Standards
- Norfloxacin EP Impurity G (CAS 70459-04-0)
- Norfloxacin EP Impurity E (CAS 75001-85-3)
- Norfloxacin EP Impurity F (CAS 67681-84-9)
- Norfloxacin Impurity 65 (CAS CATO-C4X-146865)
- Norfloxacin Piperazinyl-1-Oxide (CAS 1796931-70-8)
- Norfloxacin Impurity 22 (CAS 109142-49-6)
- Norfloxacin Impurity 50 (CAS CATO-C4X-146850)
- Norfloxacin Impurity 31 (CAS CATO-C4X-146831)
Recommended Standards
- N-(5-(Isopropylthio)-1,3,4-thiadiazol-2-yl)-3-(trifluoromethyl)benzamide (CAS 393567-48-1)
- Quinolone analog 13 (CAS CATO-C4X-1074149)
- N-(4-fluorobenzyl)-2-(2-phenylacetyl)benzamide (CAS 329079-85-8)
- Gatifloxacin Impurity 29 (CAS CATO-C4X-125329)
- Ibrutinib Impurity 104 (CAS CATO-C4X-1064104)
- Desoximetasone Impurity 5 (CAS 4306-57-4)
- Roxatidine Impurity 34 (CAS 15504-60-6)
- Ethyl Methyl Sulfate (CAS 814-40-4)
- Prucalopride Impurity 42 (CAS CATO-C4X-103842)
- 2-Chloro-N-(2,3-dihydro-benzo[1,4]dioxin-5-ylmethyl)-N-isopropyl-acetamide (CAS 1175750-26-1)
- Salbutamol Impurity 218 (CAS CATO-C4X-1176218)
- tert-Butyl 2-Amino-4-(4-methyl-1-piperazinyl)benzoate (CAS 1034975-35-3)
- 3-Chloromethyl-2-fluoro-5-(trifluoromethyl)pyridine (CAS 1227561-85-4)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com