1,1-Difluorospiro[2.5]octan-6-one CAS 1513853-81-0
| CAS No. | 1513853-81-0 |
| Molecular Formula | C8H10F2O |
| Molecular Weight | 160.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1,1-Difluorospiro[2.5]octan-6-one (C8H10F2O) contains a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 160.16 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1,1-Difluorospiro[2.5]octan-6-one (CAS 1513853-81-0), molecular formula C8H10F2O and molecular weight 160.16 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,1-Difluorospiro[2.5]octan-6-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10F2O |
| Molecular Weight | 160.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Difluorospiro Standards
- 6,6-Difluorospiro[3.3]heptane-2-carbaldehyde (CAS 2253638-83-2)
- 6,6-Difluorospiro[2.5]octan-1-amine (CAS 1461706-22-8)
- (2,2-Difluorospiro[3.3]heptan-6-yl)methanamine (CAS 1638920-27-0)
- 1,1-Difluorospiro[2.5]octan-6-amine (CAS 1782325-38-5)
- 1-(1,1-Difluorospiro[2.3]Hexan-5-yl)-N-methylmethanamine (CAS 2092713-01-2)
- 1,1-Difluorospiro[2.5]Octan-5-amine (CAS 2306264-20-8)
- 2,2-Difluorospiro[2.3]Hexane-1-carboxylic acid (CAS 1936230-67-9)
- 1,1-difluorospiro[2.3]hexane-5-carboxylic acid (CAS 1955514-17-6)
Recommended Standards
- rel-(3aR,6aS)-5,5-Difluorohexahydropentalen-2(1H)-one (CAS 1447943-05-6)
- 7,7-Difluoro-1-methylbicyclo[4.1.0]heptan-3-one, 97% (CAS 1557247-48-9)
- 1-Ethynyl-4,4-difluorocyclohexan-1-ol (CAS 1446099-82-6)
- 2-(3,3-Difluoropiperidin-4-yl)acetonitrile (CAS 1782516-55-5)
- (4-(2-Aminoethyl)piperazin-1-yl)(cyclopentyl)methanone (CAS 1094880-41-7)
- N-(2,4-dichlorobenzyl)-1-(piperidin-4-yl)methanamine hydrochloride (CAS 1261229-69-9)
- Lenalidomide-PEG1-C2-azide (CAS 2399455-45-7)
- 2,2-Difluoropropane-1,3-diamine dihydrochloride (CAS 133186-53-5)
- (4-Aminopiperidin-1-yl)(o-tolyl)methanone (CAS 1158359-06-8)
- 4-Amino-5-chloro-8-methoxyquinoline-3-carbohydrazide (CAS 1315374-21-0)
- 1-(3-acetylphenyl)pyrrolidin-2-one (CAS 765917-13-3)
- Boc-2,4-difluoro-D-phenylalanine (CAS 167993-24-0)
- 4-Methoxy-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine (CAS 1200132-24-6)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
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