1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-5-carbonitrile CAS 151387-94-9
| CAS No. | 151387-94-9 |
| Molecular Formula | C15H7ClF3N3 |
| Molecular Weight | 321.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-5-carbonitrile.
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-5-carbonitrile (CAS 151387-94-9) is a high-purity analytical reference standard with the molecular formula C15H7ClF3N3 and a molecular weight of 321.68 g/mol.
The molecular framework of 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-5-carbonitrile (C15H7ClF3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H7ClF3N3 |
| Molecular Weight | 321.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Methyl 5-chloro-2-{[(E)-4,4,4-trifluoro-1-methyl-3-oxo-1-butenyl]amino}benzenecarboxylate (CAS 1210908-67-0)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-3-carbonitrile (CAS 151388-01-1)
- (2Z)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(ethoxymethylidene)butane-1,3-dione (CAS 900014-69-9)
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Recommended Standards
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- 8-Chloro-2-(3-propoxyphenyl)quinoline-4-carboxylic acid (CAS 862713-32-4)
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- 3-Fluoro-4-methyl-2-nitroaniline (CAS 1806492-39-6)
- 1-(4-(tert-butyl)phenyl)-4,4,4-trifluorobutane-1,3-dione (CAS 94856-12-9)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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