(2Z)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(ethoxymethylidene)butane-1,3-dione CAS 900014-69-9
| CAS No. | 900014-69-9 |
| Molecular Formula | C13H11ClF3NO3 |
| Molecular Weight | 321.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2Z)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(ethoxymethylidene)butane-1,3-dione (CAS 900014-69-9) is a high-purity analytical reference standard with the molecular formula C13H11ClF3NO3 and a molecular weight of 321.68 g/mol.
(2Z)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(ethoxymethylidene)butane-1,3-dione (C13H11ClF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures (2Z)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(ethoxymethylidene)butane-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11ClF3NO3 |
| Molecular Weight | 321.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Z Standards
- Methyl 5-chloro-2-{[(E)-4,4,4-trifluoro-1-methyl-3-oxo-1-butenyl]amino}benzenecarboxylate (CAS 1210908-67-0)
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- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole-3-carbonitrile (CAS 151388-01-1)
- 1-(5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazol-3-yl)ethan-1-one (CAS 338422-57-4)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-[(1E)-(methoxyimino)methyl]pyrrolidin-2-one (CAS 866051-42-5)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N'-[(2E)-3-oxobutan-2-ylidene]acetohydrazide (CAS 400084-53-9)
- 3-Chloro-2-(5-(dimethoxymethyl)-1H-pyrazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 318958-91-7)
- 4-(8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)benzonitrile (CAS 1980053-72-2)
Recommended Standards
- (R)-3-(2,2,2-Trifluoroacetamido)-2,3-dihydro-1H-inden-5-yl 2-chloroacetate (CAS 209394-88-7)
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- 2-(4-Chlorophenyl)-3-(trifluoromethyl)benzofuran-5-carbonitrile (CAS 821770-06-3)
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- 3-(2-Methylpropyl)-1H-1,2,4-triazole (CAS 40515-29-5)
- 4-(1,1-Difluoroethyl)aniline (CAS 1379282-27-5)
- (2-Morpholinoethyl)triphenylphosphonium bromide (CAS 21331-68-0)
- 4-Bromo-1-(chloromethyl)-2-(trifluoromethyl)benzene (CAS 1214350-42-1)
- 2-((4,6-Bis((4-chlorophenyl)amino)-1,3,5-triazin-2-yl)amino)acetic acid (CAS 62751-91-1)
- Hexapeptide-10 (CAS 146439-94-3)
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