| CAS No. | 1514-87-0 |
| Molecular Formula | C3H3ClF2O2 |
| Molecular Weight | 144.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 144.50 g/mol gives Methyl chlorodifluoroacetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl chlorodifluoroacetate (CAS 1514-87-0) is a high-purity analytical reference standard with the molecular formula C3H3ClF2O2 and a molecular weight of 144.50 g/mol.
Methyl chlorodifluoroacetate (C3H3ClF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C3H3ClF2O2 |
| Molecular Weight | 144.50 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |