3-Chloro-3,3-difluoropropanoic acid CAS 76140-45-9
| CAS No. | 76140-45-9 |
| Molecular Formula | C3H3ClF2O2 |
| Molecular Weight | 144.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 144.50 g/mol gives 3-Chloro-3,3-difluoropropanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-3,3-difluoropropanoic acid (CAS 76140-45-9), molecular formula C3H3ClF2O2 and molecular weight 144.50 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C3H3ClF2O2, 3-Chloro-3,3-difluoropropanoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 144.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-3,3-difluoropropanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3H3ClF2O2 |
| Molecular Weight | 144.50 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-chloro-1,1,2-trifluorocyclobutane (CAS 38310-68-8)
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Recommended Standards
- Methyl chlorodifluoroacetate (CAS 1514-87-0)
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- 3-Chloro-5-hydroxy-4-iodobenzoic acid (CAS 2385054-24-8)
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- 2-Chloroallyl acetate (CAS 692-72-8)
- Azetidin-1-yl(5-bromo-6-chloropyridin-2-yl)methanone (CAS 2166946-61-6)
- 3-[(2-aminophenyl)sulfanyl]propanenitrile (CAS 4327-52-0)
- 4-Bromo-2-isopropoxypyrimidine (CAS 959240-85-8)
- Methyl 3,4,5-trichlorobenzoate (CAS 114821-66-8)
- [Ac-Cys4,DPhe7,Cys10] a-MSH (4-13), amide (CAS 91050-39-4)
- Ethyl 3-amino-4,4-dimethylpentanoate (CAS 197904-09-9)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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