Agomelatine Impurity 5 CAS 152302-45-9
| CAS No. | 152302-45-9 |
| Molecular Formula | C14H15NO2 |
| Molecular Weight | 229.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Agomelatine Impurity 5 (CAS 152302-45-9), a pharmacopoeial impurity reference standard (molecular formula C14H15NO2, MW 229.27 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Agomelatine Impurity 5 (C14H15NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15NO2 |
| Molecular Weight | 229.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
Related Agomelatine Standards
- Agomelatine Impurity 48 (CAS CATO-C4X-110848)
- Agomelatine Impurity 46 (CAS 1607465-50-8)
- Agomelatine Impurity 26 (CAS 945853-23-6)
- Agomelatine Impurity 44 (CAS 55917-07-2)
- Agomelatine Impurity 17 (CAS 92041-01-5)
- Agomelatine Impurity 10 (CAS 20176-04-9)
- Agomelatine Impurity 34 (CAS 27533-69-3)
- Agomelatine Impurity 43 (CAS CATO-C4X-110843)
Recommended Standards
- Atorvastatin Impurity 32 (CAS 186508-94-1)
- (1R,4S)-4-(hydroxymethyl)-2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylic acid tert-butyl ester (CAS 2643374-05-2)
- Atorvastatin Impurity 62 (CAS 125971-93-9)
- (1S,4R)-4-(hydroxymethyl)-2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate tert-butyl ester (CAS 2643374-00-7)
- Ceritinib Impurity 60 (CAS CATO-C4X-104860)
- Valnemulin impurity 5 (CAS CATO-C4X-19995)
- Biperiden EP Impurity E (CAS 2832847-11-5)
- Potassium 2-iodophenyltrifluoroborate (CAS 1431616-58-8)
- 6-Chloro-4-methoxynicotinaldehyde (CAS 1256823-05-8)
- (Deamino-Cys1,D-Arg8)-Vasopressin (CAS 16679-58-6)
- 3-(Allyloxy)-2-bromopyridine (CAS 123552-77-2)
- 2-Chloro-1-[1-(2-methoxyethyl)-2,5-dimethyl-1H-pyrrol-3-yl]ethan-1-one (CAS 379241-47-1)
- Ethyl 2-(4-(2,5-dihydro-1H-pyrrol-1-yl)phenyl)acetate (CAS 59235-27-7)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com