Zolmitriptan EP Impurity E CAS 152305-23-2
| CAS No. | 152305-23-2 |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.21 g/mol gives Zolmitriptan EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Zolmitriptan EP Impurity E (CAS 152305-23-2, C10H12N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Zolmitriptan EP Impurity E (C10H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Zolmitriptan EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 2 |
Related Zolmitriptan Standards
- Zolmitriptan Impurity 9 (CAS 340041-89-6)
- Zolmitriptan Impurity 41 (CAS CATO-C4X-135141)
- Zolmitriptan Impurity 42 (CAS CATO-C4X-135142)
- Zolmitriptan Impurity 38 (CAS CATO-C4X-135138)
- Zolmitriptan USP Related Compound H (CAS 1116-77-4)
- Zolmitriptan Impurity 7 (CAS 171550-12-2)
- Zolmitriptan Impurity 3 (CAS 340041-92-1)
- Zolmitriptan Impurity 27 (CAS CATO-C4X-135127)
Recommended Standards
- Agomelatine impurity 40 (CAS CATO-C4X-110840)
- Linagliptin Impurity 126 (CAS CATO-C4X-1101126)
- Rivaroxaban Impurity 83 (CAS 1456733-00-8)
- Raltitrexed Impurity 46 (CAS CATO-C4X-138646)
- Apremilast impurity 9 (CAS CATO-C4X-10099)
- Butylphthalide Impurity 82 (CAS CATO-C4X-181382)
- Atosiban Impurity 98 (CAS CATO-C4X-229398)
- Tetracaine Impurity 37 (CAS 512175-79-0 (free base))
- 5'-Isopropyl-2'-methyl-1h,2'h-[3,3'-bi(1,2,4-triazol)]-5-amine (CAS 1341625-67-9)
- D-Nebivolol (SR,RR) (CAS 118457-15-1)
- Docetaxel Impurity 43 (CAS 114915-19-4)
- (Z)-1-(2-Bromovinyl)-2-nitrobenzene (CAS 209259-55-2)
- Moxifloxacin impurity 117 (CAS 1585176-91-5)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
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