Apremilast impurity 9 CAS CATO-C4X-10099
| CAS No. | CATO-C4X-10099 |
| Molecular Formula | C22H24N2O7S |
| Molecular Weight | 460.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Apremilast impurity 9 (CAS CATO-C4X-10099), a pharmacopoeial impurity reference standard (molecular formula C22H24N2O7S, MW 460.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Apremilast impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Apremilast impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O7S |
| Molecular Weight | 460.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
Recommended Standards
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- Ethyl 2-(9H-purin-8-yl)acetate (CAS 1601084-36-9)
- 3-(4-Fluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride (CAS 1188264-40-5)
- 1-(1-((Tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)ethan-1-one (CAS 1340331-84-1)
- methyl 1-fluoro-2-oxo-cyclohexanecarboxylate (CAS 84131-42-0)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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