Tadalafil Impurity 18 CAS 153-94-6
| CAS No. | 153-94-6 |
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | 204.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tadalafil Impurity 18 (C11H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 204.23 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Tadalafil Impurity 18 (CAS 153-94-6), a pharmacopoeial impurity reference standard (molecular formula C11H12N2O2, MW 204.23 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tadalafil Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | 204.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Tadalafil Standards
- Tadalafil Impurity 163 (CAS CATO-C4X-1087163)
- Tadalafil Impurity 116 (CAS 154030-29-2)
- Tadalafil Impurity 131 (CAS 209120-51-4)
- Tadalafil Impurity 132 (CAS CATO-C4X-1087132)
- Tadalafil Impurity 73 (CAS 326-61-4)
- Tadalafil Impurity 118 (CAS CATO-C4X-1087118)
- Tadalafil Impurity 36 (CAS 4299-70-1)
- Tadalafil Impurity 49 (CAS 1379883-12-1)
Recommended Standards
- 4-Hydroxyantipyrine (CAS 1672-63-5)
- Dabigatran Impurity 83 (CAS 218168-58-2)
- 1-benzylpiperazine-2,6-dione (CAS 69370-99-6)
- Minodronic Impurity 1 (CAS 21755-34-0)
- Papaverine EP Impurity F (CAS 139-76-4)
- Tretinoin lmpurity 20 (CAS 173449-96-2)
- Paroxetine EP Impurity J HCl (CAS CATO-C4X-103572)
- 3-Fluoro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 1196151-63-9)
- 3-Cyclopropyl-4-methyl-1H-pyrazole-5-carboxylic acid (CAS 1867157-28-5)
- (S)-3-(Boc-amino)-4-(3,4-dichlorophenyl)butanoic Acid (CAS 270063-51-9)
- Cloxacillin Impurity 9 (CAS CATO-C4X-15979)
- N-Cyclopropyl-2-methylpiperidine-3-carboxamide (CAS 1706432-48-5)
- [(2-Ethoxyphenyl)methyl](2-methoxyethyl)amine (CAS 827328-44-9)
- Peptide 438 (CAS CATO-CPTD788438)
Why CATO?
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