Tadalafil Impurity 118 CAS CATO-C4X-1087118
| CAS No. | CATO-C4X-1087118 |
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tadalafil Impurity 118 (C11H12O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Tadalafil Impurity 118 (CAS CATO-C4X-1087118), a pharmacopoeial impurity reference standard (molecular formula C11H12O3, MW 192.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tadalafil Impurity 118 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Tadalafil Standards
- Tadalafil Impurity 132 (CAS CATO-C4X-1087132)
- Tadalafil Impurity 73 (CAS 326-61-4)
- Tadalafil Impurity 99 (CAS 114152-23-7)
- Tadalafil Impurity 131 (CAS 209120-51-4)
- Tadalafil Impurity 116 (CAS 154030-29-2)
- Tadalafil Impurity 135 (CAS CATO-C4X-1087135)
- Tadalafil Impurity 18 (CAS 153-94-6)
- Tadalafil Impurity 10 (CAS 100077-49-4)
Recommended Standards
- Edaravone Impurity 17 (CAS CATO-C4X-106217)
- Rivaroxaban impurity 193 (CAS CATO-C4X-1090193)
- Edaravone Impurity 11 (CAS CATO-C4X-106211)
- Rivaroxaban Impurity 32 (CAS 438056-69-0)
- Haloperidol Impurity 01 HCl (CAS 173447-88-6)
- N-Nitroso Bilastine impurity 130 (CAS CATO-C4X-2253130)
- Thioctic Acid Impurity 49 (CAS 120476-62-2)
- Methyl 2-((tert-butoxycarbonyl)amino)pent-4-enoate (CAS 106928-50-1)
- m-PEG24-azide (CAS 2563873-82-3)
- 1-(3-Aminocyclobutyl)-3-pyrrolidinol (CAS 1523096-35-6)
- Guaiacol EP Impurity C (CAS 91-16-7)
- 2-[8-(piperazin-1-yl)imidazo[1,2-a]pyridin-2-yl]acetic acid (CAS 1505993-06-5)
- Methyl (2E)-2-cyano-3-[2-(piperidin-1-yl)-1,3-thiazol-5-yl]prop-2-enoate (CAS 477868-73-8)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com