(S)-Azelastine Hydrochloride CAS 153408-27-6
| CAS No. | 153408-27-6 |
| Molecular Formula | C22H24ClN3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(S)-Azelastine Hydrochloride (C22H24ClN3OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(S)-Azelastine Hydrochloride (CAS 153408-27-6), molecular formula C22H24ClN3OHCl and molecular weight 418.36 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24ClN3O HCl |
| Molecular Weight | 418.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related S Standards
- Azelastine EP Impurity E (Z-Isomer) (CAS 105279-16-1)
- Azelastine Impurity 46 (CAS 109386-70-1)
- Azelastine EP Impurity B (CAS 110406-94-5)
- Azelastine Impurity 52 (CAS 1107016-94-3)
- Azelastine USP RC B HCI (CAS 117078-69-0)
- Azelastine Impurity 30 (CAS 117078-70-3)
- Azelastine-13C,d3 (CAS 1217019-80-1)
- Azelastine Impurity 17 (CAS 1239312-56-1)
Recommended Standards
- (S)-3-Amino-3-(4-(trifluoromethyl)phenyl)propan-1-ol (CAS 1212866-01-7)
- 2-Fluoro-2-phenylcyclopropan-1-amine (CAS 914221-39-9)
- ethyl 7-methylimidazo[1,2-a]pyrimidine-2-carboxylate (CAS 76075-24-6)
- Triallyl Isocyanurate (stabilized with BHT) (CAS 1025-15-6)
- 1-(6-Iodo-7-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-1-yl)-2,2-dimethylpropan-1-one (CAS 1261365-43-8)
- 26- Hydroxycholesterol (CAS 13095-61-9)
- 2,3-Bis[(2S,5S)-2,5-dimethylphospholanyl]maleic anhydride(1,5-cyclooctadiene)rhodium (I) tetrafluoroborate (CAS 821793-39-9)
- 2-Amino-5-chloropyrimidine-4-carboxylic acid hydrochloride (CAS 1588441-24-0)
- Carbidopa EP Impurity D (CAS 934371-48-9)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com