(R)-Azelastine Hydrochloride CAS 153408-28-7
| CAS No. | 153408-28-7 |
| Molecular Formula | C22H24ClN3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-Azelastine Hydrochloride.
CATO supplies (R)-Azelastine Hydrochloride (CAS 153408-28-7), a certified reference material (molecular formula C22H24ClN3OHCl, MW 418.36 g/mol) for analytical method development and quality control.
Based on its molecular formula C22H24ClN3OHCl, (R)-Azelastine Hydrochloride contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 418.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (R)-Azelastine Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24ClN3O HCl |
| Molecular Weight | 418.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related R Standards
- Azelastine EP Impurity E (Z-Isomer) (CAS 105279-16-1)
- Azelastine Impurity 46 (CAS 109386-70-1)
- Azelastine EP Impurity B (CAS 110406-94-5)
- Azelastine Impurity 52 (CAS 1107016-94-3)
- Azelastine USP RC B HCI (CAS 117078-69-0)
- Azelastine Impurity 30 (CAS 117078-70-3)
- Azelastine-13C,d3 (CAS 1217019-80-1)
- Azelastine Impurity 17 (CAS 1239312-56-1)
Recommended Standards
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- (3-((4,5-Dihydrothiazol-2-yl)carbamoyl)phenyl)boronic acid (CAS 871333-06-1)
- 7-iodo-5H-pyrrolo[2,3-b]pyrazine (CAS 889451-26-7)
- 2-Fluoro-4-(3-(trifluoromethyl)-benzyloxy)benzonitrile (CAS 1240309-68-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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