Labetalol Impurity 68 CAS CATO-C4X-246668
| CAS No. | CATO-C4X-246668 |
| Molecular Formula | C10H9ClO4 |
| Molecular Weight | 228.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Labetalol Impurity 68 (CAS CATO-C4X-246668), a pharmacopoeial impurity reference standard (molecular formula C10H9ClO4, MW 228.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Labetalol Impurity 68 (C10H9ClO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H9ClO4 |
| Molecular Weight | 228.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Labetalol Standards
- Labetalol Impurity 21 (CAS 33254-88-5)
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol Impurity 60 (CAS CATO-C4X-246660)
- Labetalol Impurity 20 (CAS 73866-23-6)
- Labetalol Impurity 79 (CAS CATO-C4X-246679)
- Labetalol EP Impurity D (CAS CATO-C1829030)
- Labetalol Impurity 66 (CAS CATO-C4X-246666)
- Labetalol Impurity 78 (CAS CATO-C4X-246678)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com