Pioglitazone impurity 38 CAS CATO-C4X-138338
| CAS No. | CATO-C4X-138338 |
| Molecular Formula | C19H18N2O3S |
| Molecular Weight | 354.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pioglitazone impurity 38 (CAS CATO-C4X-138338) is a certified pharmaceutical impurity reference standard with the molecular formula C19H18N2O3S and a molecular weight of 354.42 g/mol.
The molecular framework of Pioglitazone impurity 38 (C19H18N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pioglitazone impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18N2O3S |
| Molecular Weight | 354.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- (5Z)-Pioglitazone EP Impurity B (CAS 136401-69-9)
- Pioglitazone Impurity 6 (CAS 144809-28-9)
- Pioglitazone Impurity 21 (CAS 105355-26-8)
- Pioglitazone impurity 25 (CAS CATO-C4X-138325)
- Pioglitazone impurity 31 (CAS CATO-C4X-138331)
- Pioglitazone (CAS 111025-46-8)
- Pioglitazone impurity 53 (CAS CATO-C4X-138353)
- Pioglitazone impurity 58 (CAS CATO-C4X-138358)
Recommended Standards
- tert-butyl N-(tert-butoxycarbonylamino)-N-(4-fluoro-3,5-dimethyl-phenyl)carbamate (CAS 2212021-55-9)
- Biotin Impurity 36 (CAS 1535184-53-2)
- Tert-butyl 4-(3-(4-fluorophenoxy)-2-hydroxypropyl)piperazine-1-carboxylate (CAS 874801-05-5)
- Meloxicam-d3 (CAS 942047-63-4)
- Montelukast Impurity 2 (CAS CATO-C4X-10312)
- Iobitridol Impurity 21 (CAS CATO-C4X-317821)
- Olaparib Impurity 150 (CAS CATO-C4X-1135150)
- Ethyl 2-(3-chloropropanamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate (CAS 807355-70-0)
- Benzyl (R)-(morpholin-3-ylmethyl)carbamate hydrochloride (CAS 1881275-78-0)
- Methyl 5-amino-2-[3-(diethylamino)phenoxy]benzoate (CAS 927802-65-1)
- 1-[(1R)-1-Phenylethyl]-1H-imidazole-5-carboxylic acid-[4-[3-(trifluoromethyl)-3H-diazirin-3-yl]pheny (CAS 908024-18-0)
- Amiodarone Impurity I (CAS CATO-C4X-142515)
- (4,5-Difluoro-2-(pyrrolidin-1-ylsulfonyl)phenyl)boronic acid (CAS 1704066-91-0)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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