Oclacitinib impurity 12 CAS 1538596-97-2
| CAS No. | 1538596-97-2 |
| Molecular Formula | C15H23N5O2S |
| Molecular Weight | 337.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Oclacitinib impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Oclacitinib impurity 12 (CAS 1538596-97-2, C15H23N5O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Oclacitinib impurity 12 (C15H23N5O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 337.44 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H23N5O2S |
| Molecular Weight | 337.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Oclacitinib Standards
- Oclacitinib (CAS 1208319-26-9)
- Oclacitinib-13C-d3 (CAS CATO-C4X-301845)
- Oclacitinib Impurity 23 (CAS CATO-C4X-301823)
- Oclacitinib Impurity 19 (CAS 2124221-13-0)
- Oclacitinib impurity 8 (CAS CATO-C4X-30188)
- Oclacitinib impurity 7 (CAS CATO-C4X-30187)
- Oclacitinib Impurity 41 (CAS CATO-C4X-301841)
- Oclacitinib Impurity 43 (CAS CATO-C4X-301843)
Recommended Standards
- Abrocitinib Impurity 53 (CAS CATO-C4X-288453)
- Tert-butyl 9-(2-ethoxy-2-oxoethylidene)-3-azaspiro[5.5]Undecane-3-carboxylate (CAS 1416176-18-5)
- Undecylcholine phosphate (CAS 253678-65-8)
- Tert-butyl (E)-2-(3-ethoxy-3-oxoprop-1-en-1-yl)-8-azaspiro[4.5]Decane-8-carboxylate (CAS 1599479-34-1)
- Olaparib Impurity 18 (CAS 2250243-17-3)
- Dapagliflozin Impurity 21 (CAS CATO-C4X-113821)
- Agomelatine Impurity 9 (CAS CATO-C4X-11089)
- 7-(2-((4-Chlorobenzyl)oxy)phenyl)-2-methylpyrazolo[1,5-a]pyrimidine (CAS 439109-56-5)
- 4488-40-8 1-Naphthalenecarboxylic acid, 4-methyl- 4-Methyl-1-naphthalenecarboxylic acid (CAS 4488-40-8)
- Ethyl 7-(4-hexyloxyphenyl)-7-oxoheptanoate (CAS 898757-93-2)
- 4-(Cyclohexylmethoxy)benzaldehyde (CAS 126521-53-7)
- 4-pentyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5-trien-3-one (CAS 565171-27-9)
- Methyl (s)-3-amino-3-(5-methylfuran-2-yl)propanoate (CAS 1212818-98-8)
- Insulin Glargine (CAS 160337-95-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com