Oclacitinib impurity 8 CAS CATO-C4X-30188
| CAS No. | CATO-C4X-30188 |
| Molecular Formula | C14H21N5O2S |
| Molecular Weight | 323.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Oclacitinib impurity 8 (CAS CATO-C4X-30188) is a certified pharmaceutical impurity reference standard with the molecular formula C14H21N5O2S and a molecular weight of 323.41 g/mol.
Oclacitinib impurity 8 (C14H21N5O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Oclacitinib impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H21N5O2S |
| Molecular Weight | 323.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Oclacitinib Standards
- Oclacitinib Impurity 19 (CAS 2124221-13-0)
- Oclacitinib (CAS 1208319-26-9)
- Oclacitinib impurity 12 (CAS 1538596-97-2)
- Oclacitinib-13C-d3 (CAS CATO-C4X-301845)
- Oclacitinib Impurity 23 (CAS CATO-C4X-301823)
- Oclacitinib impurity 7 (CAS CATO-C4X-30187)
- Oclacitinib Impurity 41 (CAS CATO-C4X-301841)
- Oclacitinib Impurity 43 (CAS CATO-C4X-301843)
Recommended Standards
- Leucogen Impurity 15 (CAS CATO-C4X-288915)
- Gliclazide (CAS 21187-98-4)
- Abrocitinib Impurity 30 (CAS CATO-C4X-288430)
- Tazarotene Acid (CAS 118292-41-4)
- Hydroxychloroquine Impurity 74 (CAS 2411340-32-2)
- Lomefloxacin Impurity 1 (CAS 75338-42-0)
- Eltrombopag impurity 147 (CAS CATO-C4X-1198147)
- 6-Methylquinoline-5-carboxylic acid (CAS 1211488-26-4)
- 2-Butenedioic acid (2Z)-, polymer with methoxyethene, sodium salt (CAS 26300-19-6)
- 3-(2-(3-Methoxyphenoxy)ethyl)piperidine (CAS 946715-86-2)
- 2-Methyl-4-(methylsulfonyl)butan-1-amine (CAS 1249650-97-2)
- (2-Fluorobenzyl)hydrazine Hydrochloride (CAS 1216246-45-5)
- 2-((Tert-butoxycarbonyl)amino)-2-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)acetic acid (CAS 1822544-80-8)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
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