Rosuvastatin Impurity 154 CAS 154026-94-5
| CAS No. | 154026-94-5 |
| Molecular Formula | C13H23ClO4 |
| Molecular Weight | 278.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H23ClO4, Rosuvastatin Impurity 154 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 278.77 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Rosuvastatin Impurity 154 (CAS 154026-94-5, C13H23ClO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rosuvastatin Impurity 154 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H23ClO4 |
| Molecular Weight | 278.77 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 254 (CAS 521974-01-6)
- Rosuvastatin Impurity 86 (CAS 521973-99-9)
- Rosuvastatin Impurity 95 (CAS CATO-C4X-116995)
- Rosuvastatin Impurity 96 (CAS 521974-00-5)
- Rosuvastatin Impurity 31 (CAS 2095786-11-9)
- Rosuvastatin impurity 245 (CAS 147118-41-0)
- Rosuvastatin Impurity 78 (CAS 488798-37-4)
- Rosuvastatin Impurity 269 (CAS CATO-C4X-1169269)
Recommended Standards
- Clidanac (CAS 34148-01-1)
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- Cefotetan (CAS 69712-56-7)
- N-benzylpiperazine-1-sulfonamide hydrochloride (CAS 1171172-87-4)
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