Doripenem Impurity 3 CAS 154634-04-5
| CAS No. | 154634-04-5 |
| Molecular Formula | C29H27N2O10P |
| Molecular Weight | 594.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C29H27N2O10P, Doripenem Impurity 3 contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 594.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Doripenem Impurity 3 (CAS 154634-04-5) is a certified pharmaceutical impurity reference standard with the molecular formula C29H27N2O10P and a molecular weight of 594.51 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Doripenem Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H27N2O10P |
| Molecular Weight | 594.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 2 |
Related Doripenem Standards
- Doripenem Impurity 2 (CAS 396717-61-6)
- Doripenem Impurity 4 (CAS CATO-C4X-16214)
- Doripenem Impurity 5 (CAS 189188-38-3)
- Doripenem Impurity 17 (CAS 90776-59-3)
- Doripenem 4R Isomer Impurity (CAS 571176-82-4)
- Doripenem Impurity 12 (CAS CATO-C4X-162112)
- Doripenem Impurity 11 (CAS CATO-C4X-162111)
- Doripenem Impurity 1 (CAS 491878-07-0)
Recommended Standards
- 1-3-5-Tri-O-benzoyl-2-O-(trifluoromethanesulfonyl)-α-D-ribofuranose (CAS 97614-41-0)
- (1R,2R,4S)-1,3,3-Trimethylbicyclo[2.2.1]heptan-2-yl acetate (CAS 99341-77-2)
- Ruxolitinib Impurity 44 (CAS CATO-C4X-205844)
- 3-(((2S,3R,4S,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one (CAS 108906-96-3)
- Vitamin A Impurity 24 (CAS 1224-78-8)
- Loxoprofen Impurity 151 (CAS 1218987-96-2)
- Atracurium impurity 101 (CAS CATO-C4X-1850101)
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- 2-aminopyrimido[4,5-d]pyrimidin-4(3H)-one (CAS 89890-99-3)
- [Hydroxy(phenyl)methylene]malononitrile (CAS 5515-36-6)
- 4-Benzyl-3-chloro-4H-1,2,4-triazole (CAS 1019031-93-6)
- Dulaglutide (CAS 923950-08-7)
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