5-(Trifluoromethyl)dihydrofuran-2(3H)-one CAS 1547-45-1

Description

The occurrence of 5-(Trifluoromethyl)dihydrofuran-2(3H)-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(Trifluoromethyl)dihydrofuran-2(3H)-one (CAS 1547-45-1) is a high-purity analytical reference standard with the molecular formula C5H5F3O2 and a molecular weight of 154.09 g/mol.

5-(Trifluoromethyl)dihydrofuran-2(3H)-one (C5H5F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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