2-(2,2-Difluoroethoxy)acetonitrile CAS 1553618-82-8
| CAS No. | 1553618-82-8 |
| Molecular Formula | C4H5F2NO |
| Molecular Weight | 121.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2,2-Difluoroethoxy)acetonitrile is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(2,2-Difluoroethoxy)acetonitrile (CAS 1553618-82-8), a certified reference material (molecular formula C4H5F2NO, MW 121.09 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2,2-Difluoroethoxy)acetonitrile (C4H5F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2,2-Difluoroethoxy)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H5F2NO |
| Molecular Weight | 121.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethoxy Standards
- 2-(2,2-Difluoroethoxy)ethan-1-ol (CAS 853005-07-9)
- 3-(2,2-Difluoroethoxy)propanenitrile (CAS 1309602-19-4)
- 3-(2,2-Difluoroethoxy)azetidine (CAS 1342279-77-9)
- 3-(2,2-Difluoroethoxy)propanal (CAS 1556788-85-2)
- 3-(2,2-Difluoroethoxy)propan-1-amine (CAS 1250067-99-2)
- (2, 2- Difluoroethoxy) acetic Acid (CAS 269731-26-2)
- 3-(2,2-difluoroethoxy)propan-1-ol (CAS 1554181-29-1)
- 3-(2,2-Difluoroethoxy)cyclobutan-1-ol (CAS 1548013-54-2)
Recommended Standards
- 4-Formylfuran-2-carbonitrile (CAS 1369347-89-6)
- 3,3-Difluoro-2-pyrrolidinone (CAS 162970-49-2)
- D-Proline-13C5,15N (CAS 1331908-17-8)
- 4,4-Difluoropyrrolidin-2-one (CAS 1785332-67-3)
- 2,5-Diamino-1,3-benzenedisulfonic Acid (CAS 6409-48-9)
- N-(5-chloro-2-methoxyphenyl)-4-(2,4-dichlorophenoxy)butanamide (CAS 303091-82-9)
- 3-(Triallylsilyl)propyl acrylate (CAS 1990509-29-9)
- Hirsuteine (CAS 35467-43-7)
- 6-Bromo-7-(3-((tert-butyldimethylsilyl)oxy)propyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 821794-85-8)
- (E)-N-(Dihydrofuran-2(3H)-ylidene)-4-methylaniline (CAS 61218-61-9)
- 5-(Ethylsulfonyl)-4-(3-fluorophenyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1710833-71-8)
- Europium(III) nitrate hydrate (CAS 100587-95-9)
- tert-Butyl (5,6-difluoro-9H-pyrido[2,3-b]indol-8-yl)(methyl)carbamate (CAS 2245358-35-2)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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