2-Bromo-1-(2-chloro-6-fluorophenyl)ethanone CAS 157359-99-4

Purity 97%+In StockPharmaceutical Standards
CAS No.157359-99-4
Molecular FormulaC8H5BrClFO
Molecular Weight251.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-1-(2-chloro-6-fluorophenyl)ethanone CAS 157359-99-4 chemical structure

Description

The occurrence of 2-Bromo-1-(2-chloro-6-fluorophenyl)ethanone is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Bromo-1-(2-chloro-6-fluorophenyl)ethanone (CAS 157359-99-4), molecular formula C8H5BrClFO and molecular weight 251.48 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C8H5BrClFO, 2-Bromo-1-(2-chloro-6-fluorophenyl)ethanone contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 251.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Bromo-1-(2-chloro-6-fluorophenyl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5BrClFO
Molecular Weight251.48 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2001
Halogen ContentF/Cl/Br-containing

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