Irinotecan EP Impurity A HCl Trihydrate CAS 158406-44-1
| CAS No. | 158406-44-1 |
| Molecular Formula | C31H34N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Irinotecan EP Impurity A HCl Trihydrate (CAS 158406-44-1), a pharmacopoeial impurity reference standard (molecular formula C31H34N4O6HClH2O, MW 613.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C31H34N4O6HClH2O, Irinotecan EP Impurity A HCl Trihydrate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 613.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Irinotecan EP Impurity A HCl Trihydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H34N4O6 HCl 3*H2O |
| Molecular Weight | 613.11 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Irinotecan Standards
- Irinotecan Hydrochloride (CAS 100286-90-6)
- Irinotecan Impurity 70 (CAS 100286-91-7)
- Irinotecan Impurity 69 (CAS 100286-92-8)
- Irinotecan Impurity 72 (CAS 100286-93-9)
- Irinotecan Impurity 71 (CAS 100286-94-0)
- Irinotecan Impurity N1 (CAS 1026078-50-1)
- Irinotecan EP Impurity A (CAS 103816-16-6)
- Irinotecan Impurity 14 (CAS 110351-94-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com