Irinotecan Impurity 70 CAS 100286-91-7
| CAS No. | 100286-91-7 |
| Molecular Formula | C13H6N3NaO5S |
| Molecular Weight | 339.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Irinotecan Impurity 70 (CAS 100286-91-7), a pharmacopoeial impurity reference standard (molecular formula C13H6N3NaO5S, MW 339.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H6N3NaO5S, Irinotecan Impurity 70 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 339.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Irinotecan Impurity 70 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H6N3NaO5S |
| Molecular Weight | 339.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Irinotecan Standards
- Irinotecan Impurity 49 (CAS 177611-40-4)
- Irinotecan Impurity 59 (CAS CATO-C4X-166759)
- Irinotecan Hydrochloride Trihydrate EP Impurity B (CAS 19685-09-7)
- Irinotecan Impurity 9 (CAS 80758-83-4)
- Irinotecan EP Impurity F (CAS 78287-27-1)
- Irinotecan Impurity 23 (CAS 1217633-65-2)
- Irinotecan Impurity 8 (CAS 78287-14-6)
- Irinotecan Impurity 56 (CAS 797762-11-9)
Recommended Standards
- N-{1-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl}ethanesulfonamide (CAS 2246431-33-2)
- 1-Oxo-2-(3-(trifluoromethyl)phenyl)-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 1005068-67-6)
- N,N-Diethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 911228-95-0)
- N'-(4-methoxybenzoyl)-6-(trifluoromethyl)nicotinohydrazide (CAS 1092346-04-7)
- Terazosin EP Impurity F HCl (CAS 109678-71-9(Free Base))
- Rebamipide Impurity 64 (CAS CATO-C4X-152364)
- Ibrutinib Impurity 63 (CAS CATO-C4X-106463)
- Metenolone Enanthate (CAS 303-42-4)
- 2,5-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 945117-31-7)
- Perfluorophenyl trifluoromethanesulfonate (CAS 60129-85-3)
- 2-{[5-(2,4-dichlorophenyl)-4-ethyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 337487-69-1)
- 2-((2-Aminoethyl)(6-((5-cyanopyrazin-2-yl)amino)pyrimidin-4-yl)amino)acetamide (CAS 1137475-09-2)
- Li Standard Solution (CAS 7439-93-2)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
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