Rapamycin Impurity 11 CAS 159351-88-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.159351-88-9
Molecular FormulaC52H81NO13
Molecular Weight928.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rapamycin Impurity 11 CAS 159351-88-9 chemical structure

Description

As a certified reference material (CRM), Rapamycin Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Rapamycin Impurity 11 (CAS 159351-88-9) is a certified pharmaceutical impurity reference standard with the molecular formula C52H81NO13 and a molecular weight of 928.20 g/mol.

Structurally, Rapamycin Impurity 11 (C52H81NO13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 928.20 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC52H81NO13
Molecular Weight928.20 g/mol
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Nitrogen Atoms1

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