Everolimus Impurity 44 CAS 159351-77-6
| CAS No. | 159351-77-6 |
| Molecular Formula | C55H87NO15 |
| Molecular Weight | 1002.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Everolimus Impurity 44 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 1002.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Everolimus Impurity 44 (CAS 159351-77-6) is a certified pharmaceutical impurity reference standard with the molecular formula C55H87NO15 and a molecular weight of 1002.28 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Everolimus Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C55H87NO15 |
| Molecular Weight | 1002.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus Impurity 35 (CAS CATO-C4X-112235)
- Everolimus Impurity 43 (CAS CATO-C4X-112243)
- Everolimus Impurity 7 (CAS CATO-C4X-11227)
- Everolimus Impurity 32 (CAS CATO-C4X-112232)
- Everolimus Impurity 38 (CAS CATO-C4X-112238)
- Everolimus Impurity 40 (CAS CATO-C4X-112240)
- Everolimus Impurity 48 (CAS CATO-C4X-112248)
- Everolimus Impurity 37 (CAS 769905-89-7)
Recommended Standards
- Zinc 2,11,20,29-tetra-tert-butyl-2,3-naphthalocyanine (CAS 39049-43-9)
- MZ 1 (CAS 1797406-69-9)
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- Lenacapavir Impurity 31 (CAS CATO-C4X-324831)
- Indocyanine Green Impurity 3 (CAS CATO-C4X-25033)
- Alvimopan Impurity 21 (CAS CATO-C4X-114521)
- Oseltamivir Impurity 153 (CAS CATO-C4X-1720153)
- Abrocitinib Impurity 48 HBr (CAS 1622981-00-3(free base))
- 2,2-Difluoro-3-hydroxy-3-methyl-butanoic acid (CAS 15080-23-6)
- 2,3,4,5-Tetrahydro-1H-1-benzazepine-7-carboxylic acid (CAS 19029-09-5)
- 4-((3-Methacrylamidopropyl)dimethylammonio)butane-1-sulfonate (CAS 83623-32-9)
- 3-(2,4,5-Trifluorophenyl)azetidin-3-ol (CAS 1862993-82-5)
- Sitafloxacin impurity 59 (CAS 1542764-78-2)
- Peptide 441 (CAS CATO-CPTD788441)
Why CATO?
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