Amiodarone Impurity 34 CAS 159980-56-0
| CAS No. | 159980-56-0 |
| Molecular Formula | C20H19IO3 |
| Molecular Weight | 434.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Amiodarone Impurity 34.
Amiodarone Impurity 34 (CAS 159980-56-0) is a certified pharmaceutical impurity reference standard with the molecular formula C20H19IO3 and a molecular weight of 434.27 g/mol.
Based on its molecular formula C20H19IO3, Amiodarone Impurity 34 contains a steroid core, a hydroxyl group, an ether linkage, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 434.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amiodarone Impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H19IO3 |
| Molecular Weight | 434.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | I-containing |
Related Amiodarone Standards
- Amiodarone Impurity 41 (CAS CATO-C4X-142541)
- Amiodarone Hydrochloride EP Impurity F (CAS 147030-50-0)
- Amiodarone EP Impurity A (CAS 23551-25-9)
- Amiodarone Impurity 23 (CAS CATO-C4X-142523)
- Amiodarone Impurity 49 (CAS CATO-C4X-142549)
- Amiodarone Impurity 19 (CAS CATO-C4X-142519)
- Amiodarone EP Impurity C (CAS 85642-08-6)
- Amiodarone Impurity 50 (CAS CATO-C4X-142550)
Recommended Standards
- N-[3-(Dimethylamino)Propyl]-1,1,2,2,3,3,4,4,5,5,5-Undecafluoropentane-1-Sulphonamide (CAS 68555-78-2)
- Itraconazole Impurity 12 (CAS 67914-84-5)
- 2-Amino-5-(4-bromophenyl)-5-[(3,4,5-trimethoxyphenyl)methyl]-4,5-dihydro-1H-imidazol-4-one (CAS 1354918-47-0)
- AGK 2 (CAS 304896-28-4)
- Ibrutinib Impurity 159 (CAS CATO-C4X-1064159)
- Chlorpromazine Impurity 21 (CAS 68962-15-2)
- Risdiplam Impurity 1 (CAS CATO-C4X-30121)
- Methyl (S)-2-amino-2-cyclobutylacetate hydrochloride (CAS 1983066-39-2)
- (1-Ethylazetidin-3-yl)methanamine (CAS 1412978-07-4)
- N-(2-Aminoethyl)-N'-methyl-sulfamide (CAS 1596113-40-4)
- Dimethyl 2,2'-((2-((tert-butoxycarbonyl)amino)ethyl)azanediyl)diacetate (CAS 212143-39-0)
- (3-(Benzyloxy)isoxazol-5-yl)methanol (CAS 123320-44-5)
- 2-Bromo-5-chloro-1,6-naphthyridine (CAS 1260670-95-8)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com