2-chloro-3-pyridyl 4-(trifluoromethyl)benzene-1-sulphonate CAS 219930-36-6

Purity 97%+In StockPharmaceutical Standards
CAS No.219930-36-6
Molecular FormulaC12H7ClF3NO3S
Molecular Weight337.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-chloro-3-pyridyl 4-(trifluoromethyl)benzene-1-sulphonate CAS 219930-36-6 chemical structure

Description

2-chloro-3-pyridyl 4-(trifluoromethyl)benzene-1-sulphonate (CAS 219930-36-6) is a high-purity analytical reference standard with the molecular formula C12H7ClF3NO3S and a molecular weight of 337.70 g/mol.

2-chloro-3-pyridyl 4-(trifluoromethyl)benzene-1-sulphonate (C12H7ClF3NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H7ClF3NO3S
Molecular Weight337.70 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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