Tenofovir disoproxil Impurity 111 CAS 1607007-18-0
| CAS No. | 1607007-18-0 |
| Molecular Formula | C18H26N10O7P2 |
| Molecular Weight | 556.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tenofovir disoproxil Impurity 111.
Tenofovir disoproxil Impurity 111 (CAS 1607007-18-0) is a certified pharmaceutical impurity reference standard with the molecular formula C18H26N10O7P2 and a molecular weight of 556.41 g/mol.
The molecular framework of Tenofovir disoproxil Impurity 111 (C18H26N10O7P2) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tenofovir disoproxil Impurity 111 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H26N10O7P2 |
| Molecular Weight | 556.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 10 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 18 (CAS 1244022-53-4)
- Tenofovir exalidex, 98% (CAS 911208-73-6)
- Tenofovir disoproxil Impurity 138 (CAS CATO-C4X-1076138)
- Tenofovir alafenamide63 (CAS CATO-C4X-179763)
- Tenofovir disoproxil Impurity 139 (CAS CATO-C4X-1076139)
- Tenofovir disoproxil Impurity 126 (CAS CATO-C4X-1076126)
- Tenofovir Disoproxil (S)-Isomer (CAS 1280130-08-6)
- Tenofovir disoproxil (CAS 201341-05-1)
Recommended Standards
- VER 155008 (CAS 1134156-31-2)
- Pretomanid Impurity 5 (CAS CATO-C4X-26065)
- 1-(3-(1H-Imidazol-4-yl)propyl)-3-(3-((5-bromopyridin-2-yl)(3,4-dichlorobenzyl)amino)propyl)thiourea (CAS 199522-35-5)
- (2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl (((2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) hydrogen phosphate (CAS 15178-66-2)
- Goserelin EP Impurity I Acetate (CAS CATO-C4X-19209)
- Tirofiban Impurity 96 (CAS CATO-C4X-125496)
- Rosuvastatin Impurity 138 (CAS CATO-C4X-1169138)
- Prednisolone Impurity 29 (CAS 106822-21-3)
- Tegoprazan Impurity 18 (CAS 942485-42-9)
- 2-(3-(Difluoromethyl)phenyl)acetic acid (CAS 1000547-15-8)
- Methyl 2,6-dichloro-5-iodopyrimidine-4-carboxylate (CAS 1136962-00-9)
- 2-(Chloromethyl)-5-(difluoromethyl)-6-iodopyridine-3-acetic acid (CAS 1805624-09-2)
- 6,11-Dihydroxy-1-methoxytetracene-5,12-dione (CAS 38156-95-5)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com