Tenofovir disoproxil Impurity 126 CAS CATO-C4X-1076126
| CAS No. | CATO-C4X-1076126 |
| Molecular Formula | C19H30N5O11P |
| Molecular Weight | 535.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tenofovir disoproxil Impurity 126 is closely related to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tenofovir disoproxil Impurity 126 (CAS CATO-C4X-1076126) is a certified pharmaceutical impurity reference standard with the molecular formula C19H30N5O11P and a molecular weight of 535.44 g/mol.
Tenofovir disoproxil Impurity 126 (C19H30N5O11P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tenofovir disoproxil Impurity 126 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H30N5O11P |
| Molecular Weight | 535.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 138 (CAS CATO-C4X-1076138)
- Tenofovir disoproxil Impurity 18 (CAS 1244022-53-4)
- Tenofovir Disoproxil (S)-Isomer (CAS 1280130-08-6)
- Tenofovir disoproxil (CAS 201341-05-1)
- Tenofovir disoproxil Impurity 111 (CAS 1607007-18-0)
- Tenofovir alafenamide Impurity 89 (CAS CATO-C4X-179789)
- Tenofovir Isopropyl Ethyl Diester (CAS 1422284-16-9)
- Tenofovir disoproxil Impurity 117 (CAS CATO-C4X-1076117)
Recommended Standards
- 5-[(4-Bromophenyl)sulfanyl]-1-methyl-3-phenyl-4-({[3-(trifluoromethyl)phenyl]sulfanyl}methyl)-1H-pyrazole (CAS 318959-33-0)
- Lasmiditan Impurity 7 (CAS CATO-C4X-24787)
- Vinorelbine Impurity 19 (CAS CATO-C4X-264219)
- 4-Nitrophenyl β-D-xylotrioside (CAS 173468-29-6)
- Ertapenem Impurity 29 (CAS 1150883-75-2)
- Zolmitriptan Impurity 32 (CAS CATO-C4X-135132)
- Ticagrelor impurity 159 (CAS 1511636-19-3)
- (S)-3-Boc-2,2-dimethyloxazolidine-4-acetaldehyde (CAS 147959-19-1)
- N-(4-Fluorophenyl)-N,2-dimethylquinazolin-4-amine (CAS 827031-62-9)
- Mal-PEG1-bromide (CAS 1823885-81-9)
- 5-Amino-1-hydroxynaphthalene-2-sulfonic acid (CAS 58596-07-9)
- 2-[(2,4-Difluorophenyl)sulfanyl]-1-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}ethan-1-one (CAS 866136-64-3)
- 4-(4-Chlorophenyl)-5-(ethylsulfonyl)thiazol-2-amine (CAS 1708179-34-3)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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