5-(Trifluoromethyl)-3,4-dihydro-2H-pyrrole-2-carboxylic acid CAS 1609965-85-6
| CAS No. | 1609965-85-6 |
| Molecular Formula | C6H6F3NO2 |
| Molecular Weight | 181.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Trifluoromethyl)-3,4-dihydro-2H-pyrrole-2-carboxylic acid (CAS 1609965-85-6), molecular formula C6H6F3NO2 and molecular weight 181.11 g/mol, is a CATO reference standard with documented purity and traceability.
5-(Trifluoromethyl)-3,4-dihydro-2H-pyrrole-2-carboxylic acid (C6H6F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(Trifluoromethyl)-3,4-dihydro-2H-pyrrole-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6F3NO2 |
| Molecular Weight | 181.11 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)piperidine-2,4-dione (CAS 1552231-27-2)
- 4-(Trifluoromethyl)piperidine-2,6-dione (CAS 356518-29-1)
- 5-Methyl-5-(trifluoromethyl)pyrrolidine-2,4-dione (CAS 1997200-27-7)
- [1-Methyl-5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]methanol (CAS 1267796-04-2)
- 2-[3-(Trifluoromethyl)-1H-1,2,4-triazol-1-yl]ethanol (CAS 1706431-23-3)
- 2-(5-(Trifluoromethyl)-1,3,4-oxadiazol-2-yl)ethan-1-amine (CAS 944898-34-4)
- 2-[3-(Trifluoromethyl)-1,2,4-oxadiazol-5-yl]ethan-1-amine (CAS 944905-86-6)
- 2-Trifluoromethyl-4-thiazolecarboxaldehyde (CAS 133046-48-7)
Recommended Standards
- 1-(6-Oxa-3-azabicyclo[3.1.0]hexan-3-yl)-2,2,2-trifluoroethanone (CAS 164931-85-5)
- 1-(2,2,2-Trifluoroethyl)pyrrolidine-2,4-dione (CAS 1513582-88-1)
- 5-Nitrobenzo[c][1,2,5]oxadiazole 1-oxide (CAS 18771-86-3)
- 1-(3,6-Dihydro-2H-1,2-Oxazin-2-Yl)-2,2,2-Trifluoroethanone (CAS 13627-94-6)
- Catharanthine Tartrate (CAS 4168-17-6)
- N-(4-Methyloxazol-2-yl)-N-(pentan-3-yl)butyramide (CAS 57068-58-3)
- 6-Bromo-8-(chloromethyl)-4-oxo-4H-1-benzopyran-3-carboxaldehyde (CAS 735321-26-3)
- Lusutrombopag Impurity 20 (CAS 30279-00-6)
- 2,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1815616-21-7)
- n-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]methyl}cyclopropanamine (CAS 791079-97-5)
- Sumatriptan D6 Format Salt (CAS 1020764-38-8(free base))
- (1-(2-Chlorophenyl)-1H-pyrazol-4-yl)methanamine (CAS 400877-18-1)
- Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate (CAS 108905-74-4)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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