Lusutrombopag Impurity 20 CAS 30279-00-6
| CAS No. | 30279-00-6 |
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lusutrombopag Impurity 20.
CATO supplies Lusutrombopag Impurity 20 (CAS 30279-00-6), a pharmacopoeial impurity reference standard (molecular formula C11H12O3, MW 192.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lusutrombopag Impurity 20 (C11H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 192.21 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 12 (CAS 2043804-10-8)
- Lusutrombopag Impurity 27 (CAS CATO-C4X-208427)
- Lusutrombopag Impurity 64 (CAS CATO-C4X-208464)
- Lusutrombopag Impurity 78 (CAS CATO-C4X-208478)
- Lusutrombopag Impurity 1 (CAS 52043-45-5)
- Lusutrombopag Impurity 5 (CAS CATO-C4X-20845)
- Lusutrombopag Impurity 42 (CAS 1367365-00-1)
- Lusutrombopag Impurity 44 (CAS 2126856-49-1)
Recommended Standards
- Berberine Impurity 26 (CAS CATO-C4X-219926)
- Ozagrel Impurity 8 (CAS 141286-90-0)
- Siponimod impurity 19 (CAS 2918890-06-7)
- Nikethamide impurity 19 (CAS CATO-C4X-186119)
- Verapamil Impurity 35 HCl (CAS 77326-93-3 (free base))
- Finerenone Impurity 275 (E-Isomer) (CAS CATO-C4X-2880275)
- Isavuconazole Impurity 209 (CAS CATO-C4X-1236209)
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- ((3AS,4R,6S,7R,7aR)-7-hydroxy-6-(4-methoxyphenoxy)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)methyl 4-methylbenzoate (CAS 1820580-75-3)
- 5-Chloro-2-(isobutylthio)pyridine (CAS 117764-96-2)
- N,N-Dimethyl-4-(p-tolyldiazenyl)aniline (CAS 3010-57-9)
- (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(6-(trifluoromethyl)pyridin-3-yl)propanoate (CAS 944805-57-6)
- 3-(piperidin-1-ylcarbonyl)benzonitrile (CAS 1003647-40-2)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
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