Ezetimibe Impurity 62 CAS 1618657-31-0
| CAS No. | 1618657-31-0 |
| Molecular Formula | C18H17FO4 |
| Molecular Weight | 316.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ezetimibe Impurity 62 (CAS 1618657-31-0, C18H17FO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Ezetimibe Impurity 62 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ezetimibe Impurity 62 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17FO4 |
| Molecular Weight | 316.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Ezetimibe Standards
- Ezetimibe Impurity 28 (CAS CATO-C4X-109828)
- Ezetimibe Impurity 95 (CAS CATO-C4X-109895)
- Ezetimibe Impurity 114 (CAS CATO-C4X-1098114)
- Ezetimibe Impurity 145 (Z-Isomer) (CAS CATO-C4X-1098145)
- Ezetimibe Impurity 35 (CAS 70627-52-0)
- Ezetimibe Impurity 116 (CAS CATO-C4X-1098116)
- Ezetimibe Impurity 98 (CAS CATO-C4X-109898)
- Ezetimibe Impurity 115 (CAS CATO-C4X-1098115)
Recommended Standards
- n-(3-Morpholinopropyl)-4-(trifluoromethyl)benzamide (CAS 942473-87-2)
- Levosimendan Impurity 55 (CAS CATO-C4X-130855)
- N-(3-Morpholinopropyl)-3-(trifluoromethyl)benzamide (CAS 717858-96-3)
- Levosimendan Impurity 6 (CAS CATO-C4X-13086)
- Clobetasol Propionate Impurity 12 (CAS 3109-01-1)
- Rivaroxaban Impurity 107 (CAS 482308-13-4)
- Neratinib Impurity 54 (CAS CATO-C4X-113454)
- 3-Cyclopropoxy-5-ethyl-4-(trifluoromethyl)pyridine (CAS 1243404-50-3)
- 3-(3-Fluorophenyl)-1,2,4-oxadiazole-5-carbaldehyde (CAS 944906-14-3)
- 3-(trifluoromethyl)cyclobutane-1-carbonitrile (CAS 2167452-22-2)
- (2,5-Dibromophenyl)diphenylphosphineoxide (CAS 1629166-79-5)
- 2,3,5,6-Tetrafluorophenyl isothiocyanate (CAS 207981-49-5)
- 2-Methyl-2-(naphthalen-1-yl)oxirane (CAS 159805-33-1)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
Why CATO?
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