Ezetimibe Impurity 95 CAS CATO-C4X-109895
| CAS No. | CATO-C4X-109895 |
| Molecular Formula | C18H20FNO3 |
| Molecular Weight | 317.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ezetimibe Impurity 95 (CAS CATO-C4X-109895), a pharmacopoeial impurity reference standard (molecular formula C18H20FNO3, MW 317.35 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ezetimibe Impurity 95 (C18H20FNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ezetimibe Impurity 95 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20FNO3 |
| Molecular Weight | 317.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 62 (CAS 1618657-31-0)
- Ezetimibe Impurity 28 (CAS CATO-C4X-109828)
- Ezetimibe Impurity 114 (CAS CATO-C4X-1098114)
- Ezetimibe Impurity 145 (Z-Isomer) (CAS CATO-C4X-1098145)
- Ezetimibe Impurity 35 (CAS 70627-52-0)
- Ezetimibe Impurity 116 (CAS CATO-C4X-1098116)
- Ezetimibe Impurity 115 (CAS CATO-C4X-1098115)
- Ezetimibe Impurity 132 (CAS CATO-C4X-1098132)
Recommended Standards
- VLX600 (CAS 327031-55-0)
- Safinamide Impurity 38 (CAS 1827614-91-4)
- Telmisartan Impurity N2 (CAS 34981-09-4)
- 2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1009266-12-9)
- Nicotinamide Impurity 10 (CAS 23111-00-4)
- Econazole Impurity 11 (CAS 4252-78-2)
- Methylprednisolone Hydrogen Succinate EP Impurity F (CAS 2376134-25-5)
- Regadenoson Impurity 11 (CAS 24723-77-1)
- 7-bromo-6,8-difluoro-quinazolin-4-ol (CAS 1698027-87-0)
- Benzyl (4-(2-chloroacetamido)cyclohexyl)(isopropyl)carbamate (CAS 1353962-46-5)
- 2-Bromo-4-(((1-methoxypropan-2-yl)amino)methyl)phenol (CAS 1247245-62-0)
- 5-Chloro-2-(2-fluoroethoxy)benzoic acid (CAS 334652-74-3)
- N-[2-(4-Methoxyphenoxy)ethyl]acetamide (CAS 540512-00-3)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com